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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH8A1
All Species:
30.91
Human Site:
S251
Identified Species:
61.82
UniProt:
Q9H2A2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2A2
NP_072090.1
487
53401
S251
A
P
H
C
K
K
L
S
L
E
L
G
G
K
N
Chimpanzee
Pan troglodytes
XP_001170111
490
53679
S254
A
P
H
C
K
K
L
S
L
E
L
G
G
K
N
Rhesus Macaque
Macaca mulatta
XP_001101362
515
55911
S279
A
P
H
C
K
K
L
S
L
E
L
G
G
K
N
Dog
Lupus familis
XP_533415
487
53149
S251
A
P
H
C
K
K
L
S
L
E
L
G
G
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH00
487
53645
S251
A
P
H
C
K
K
L
S
L
E
L
G
G
K
N
Rat
Rattus norvegicus
P13601
501
54541
V266
G
K
S
N
L
K
R
V
T
L
E
L
G
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509667
487
53578
S251
A
P
Y
C
K
K
L
S
L
E
L
G
G
K
N
Chicken
Gallus gallus
P27463
509
55791
V274
G
K
T
N
L
K
R
V
T
L
E
L
G
G
K
Frog
Xenopus laevis
Q6GNL7
902
99964
V670
A
V
S
N
V
K
K
V
S
L
E
L
G
G
K
Zebra Danio
Brachydanio rerio
Q66I21
487
53336
S251
A
P
H
C
K
K
L
S
L
E
L
G
G
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_509203
506
55370
S271
A
K
L
N
K
K
V
S
L
E
M
G
G
K
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56YU0
501
54342
V265
A
A
S
N
L
K
K
V
S
L
E
L
G
G
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
86
87.2
N.A.
89.9
38.3
N.A.
80.6
38.3
23.7
74.1
N.A.
N.A.
N.A.
49.4
N.A.
Protein Similarity:
100
94.2
89.1
95
N.A.
95.4
56.8
N.A.
90.3
55.5
36.5
87.6
N.A.
N.A.
N.A.
67.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
93.3
13.3
20
100
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
13.3
20
100
N.A.
N.A.
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
84
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
59
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
67
34
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
0
0
0
0
0
0
0
67
100
34
0
% G
% His:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
25
0
0
67
100
17
0
0
0
0
0
0
67
34
% K
% Leu:
0
0
9
0
25
0
59
0
67
34
59
34
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
42
0
0
0
0
0
0
0
0
0
0
67
% N
% Pro:
0
59
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
25
0
0
0
0
67
17
0
0
0
0
0
0
% S
% Thr:
0
0
9
0
0
0
0
0
17
0
0
0
0
0
0
% T
% Val:
0
9
0
0
9
0
9
34
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _